【Fung Ching Yu】評論

ThenNMDAR is a specific type of ionotropic glutamate receptor. The NMDA receptor is so named because the agonist molecule N-methyl-D-aspartate (NMDA) binds selectively to it, and not to other glutamatenreceptors. Activation of NMDA receptors results in the opening of an ion channel that is nonselective to cations, with a combined reversal potential near 0 mV. While the opening and closing of the ionnchannel is primarily gated by ligand binding, the current flow through the ion channel isnvoltage dependent. Extracellular magnesium (Mg2+) and zinc (Zn2+) ions can bind to specific s...