【用戶】Dio Eraclea
【年級】高二下
【評論內容】(a)Nitrofurantoin is eliminated in urine (30% to 50% unchanged). The t ½ in healthy patients is 20 min, and the t ½ in anephric patients is 60 min.(b)68% to 99% is excreted in the urine. 8% to 12% is excreted as free chloramphenicol; the remainder is excreted as inactive metabolites. Small amounts are found in bile and feces. The t ½ is about 1.5 to 4 h.(c)EliminationOral About 40% to 50% is excreted unchanged in urine (30% for Proquin XR ); 20% to 35% is recovered in feces (43% for Proquin XR ). The t ½ is about 4 h (4.5 h for Proquin XR ). Cl is about 300 mL/min.IV About 50% to 70% is ...