問題詳情

66.使用warfarin時，下列何種藥品較不會增加international normalized ratio（INR）？
(A)vitamin K
(B)fluoxetine
(C)allopurinol
(D)tamoxifen

參考答案

答案：A
難度：簡單0.767677
統計：A(684),B(21),C(27),D(60),E(0)

用户評論

【Jason Chen】評論

(A)vitamin K ㊀warfarin抗凝血→INR↓

【大仁Jason藥師】評論

(A)vitamin K ㊀w.....★★★★★★，...

【我是你的北醫前女友】評論

B.fluoxetine (CYP2D6 inhibitor)C.allopurinol (CYP1A2 inhibitor)

【RUI】評論

Prod Info tamoxifen citrate oral tablets, possibly due to inhibition of CYP2C9-mediated warfarin metabolism by tamoxifen (Boruban et al, 2006). Although a literature review of 31 patients receiving tamoxifen and warfarin did not reveal a significant increase in risk for bleeding complications, it is recommended to closely monitor INR when tamoxifen is coadministered with warfarin, particularly during tamoxifen initiation and discontinuation (Givens et al, 2009).By micromede...