【菜餅】評論

isoniazid 機轉 ★★★★★，...

【IG:Pharmabook】評論

【basic 解題+考點統整】...

【看過幫按讚 國考必上岸】評論

Isoniazid 最強統整：1. ★☆☆☆☆☆☆☆...

【passpass】評論

奉上之前上課的筆記（1）N-Acetylation代謝快有人種之基因多型性白人：慢速Acetylation：易周邊神經毒性預肪Neurotoxiaity可每天>6 mg Pyridoxine（B6）（2）N-Acetylation産物水解肝毒性代謝物：Acetylhydrazine主要代謝物：N-Acetylisoniazid（缺乏N-acetyl transferase，則無法代謝）經Catalase-peroxidase（Kat G）：得到*Isonicotinaldehyde, *Isonicotinic acid, *Isonicotinamide原文書Mechanism of Action & Basis of ResistanceIsoniazid inhibits synthesis of mycolic acids, which are essentialcomponents of mycobacterial cell walls. Isoniazid is a prodrug thatis activated by KatG, the mycobacterial cat...