【terminator812】評論

(C) 主成分及濃度相同時，ointment與cream具有相同效價：這是錯誤的敘述。Ointment的效價通常比cream高，因為ointment在皮膚上的停留時間較長，能夠提供更好的藥物吸收。

【IG:Pharmabook】評論

10th applied p.934 各選項解析 + 補充考過國考題(C)選項應該要改成主成分及濃度相同時，gel and ointment的效價高於 creams and lotionsWhen equal amounts of a corticosteroid are incorporated into ointments, gels, creams, and lotion bases, the gel and ointment preparations are generallymore active than creams and lotions(A) 主成分及劑型相同時，濃度越高效價就越高(B) 基劑添加propylene glycol或petrolatum 可提升效價Activity of corticosteroids may be enhanced by the use of a more occlusive vehicle, the addition ofpenetration-enhancing substances (i.e., petrolatum, propylene glycol)(D)主成分結構含fluorine的製劑(加F到C9)，可預防類固醇的環被代謝，效價比結構不含fluorine者高The addition of a fluorine atom at the 9 position protects the steroid ring from metabolic conversion, resulting in more potent activity. 64 下列何種類固醇藥膏最適合嬰幼兒使用？