問題詳情

24.下列何項藥品組合較不易發生藥品交互作用?
(A)valproate-phenytoin
(B)valproate-gabapentin
(C)carbamazepine-tiagabine
(D)valproate-lamotrigine

參考答案

答案:B
難度:非常困難0
統計:A(0),B(0),C(1),D(0),E(0)

用户評論

乳音奶頭嗲雞大狒狒】評論

Valproate Products may decrease the protein binding of Fosphenytoin-Phenytoin. This appears to lead to an initial increase in the percentage of unbound (free) phenytoin and to a decrease in total phenytoin concentrations. The percentage of free (unbound) phenytoin may increase, but the total phenytoin concentration may decrease. With long-term concurrent use, total phenytoin concentrations may return to pre-valproate levels or to levels higher than those observed prior to valproate.gabapentin尤甚排泄,不會與valproate有交互作用CYP3A4 Inducers ( carbamazepine)may decrease the serum concentratio...