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Life Cycle:During a blood meal, an infected mosquito (Aedes, Culex, Anopheles, Mansonia) introduces third-stage filarial larvae of Dirofilaria immitis into the skin of the definitive host, which is usually a domestic dog or coyote in the United States (although a wide variety of other animals can also be infected, including felids, mustelids, pinnipeds, beaver, horses, and humans), where they penetrate into the bite wound . In the definitive host, the L3 larvae undergo two more molts into L4 and adults. Adults reside in pulmonary arteries, and are occasionally found in the right ventricl...