【justin1999031】評論

Immune privilege is a spectrum of evolutionary adaptations that protect vital tissues with limited regenerative capacity from collateral damage by the immune response. There is evidence that heart valves are on the spectrum of immune privileged sites. The mechanism could be related to inhibition of immune cell extravasation in the context of rapid blood flow combined with the vigorous movement of the opening and closing leaflets. This also has important clinical implications for heart valve transplantation.