問題詳情
5. Phenytoin is an anticonvulsant agent with low extraction ratio and nonlinear pharmacokinetic properties. Phenytoin ismainly metabolized by CYP2C9 and partly by CYP2C 19. Phenytoin is also known to be a substrate of P-glycoprotein.Following an oral administration, picase describe how genetic polymorphism may influence the pharmacokinetic properties (interms of clearance, AUC, and brain distribution) of phenytoin and clinical outcome of epileptic treatment.(20 points; 5 points each)
參考答案
答案：C
難度：計算中-1
書單：沒有書單，新增
用户評論
【【站僕】摩檸Morning】評論
新產品的高涉入採用者，其採用過程依序經過以下階段：知曉（Awareness）→興趣（Interest）→評估（Evaluation）→試用 (Trail）、 採用（Adoption）。