【Ian】評論

54.下列阿片類藥物中，何者的結構具初級胺（primary amine）的官能基？ (A)Methadone (B)Buprenorphine (C)Dezocine (D)Loperamide專技高考◆藥師(一)◆藥理學與藥物化學- 104 年 - 104-2-藥師(一)-藥理學與藥物化學#23933

【Tsun-Jung Zho】評論

(D) Pentazocine

【蘇莉琄】評論

A.fentanylB.dezocine

【더보이즈讓我中簽】評論

鴉片類止痛劑除了dezocine為1級胺其餘皆為3級胺A basic amine is an essential feature of all opioids because, in cationic conjugate acid form, it forms an essential electrostatic bond with the Asp residue conserved in all GPCRs.ㆍWith the exception of dezocine, an opioid agonist no longer available in the U.S., only tertiary amines provide clinically significant central opioid agonist or antagonist activity.