參、共四題 Alzheimer's disease (AD) is a trajectory neurodegenerative disease that has beenproved to be one of the most common causes of dementia. Recent studies suggest thatexercise therapy may enhance cognitive functions of AD via increasing the activity ofantioxidant enzymes and synthesis of neurotrophic factors. Dr. Green designed anexperiment to examine whether aerobic exercise (AE) can increase the functions oflearning and memory of patients with AD. He recruited 30 patients with AD from alocal outpatient clinic. Before the AE therapy, all the participants took the GeneralPractitioner Assessment of Cognition (GPCOG), which assesses several abilitiesincluding (a) short- and long-term memory, (b) concentration and attention span, (c)language and communication skills, and (d) awareness of time and place (orientation).All the participants started 30-minute sessions of AE therapy three times a week forthe following 6 months. Only 25 of the 30 participants completed the AE therapy andtook the GPCOG at the end of the 6 months. The results of GPCOG on the two timepoints of the 25 participants were compared to ensure the effects of AE therapy.

【題組】1.What should Dr. Green do before/after he collected data in order to fulfill theprofessional and ethical requirements in research?