【Jason Chen】評論
Figure 2.Mechanism of action of metoclopramide. (A) Metoclopramide promotes gut motility by inhibiting presynaptic and postsynaptic D2 receptors as well as presynaptic 5-HT4 receptors. (B) Metoclopramide also produces antiemetic effects by inhibition of D2 and 5-HT3 receptors in the CTZ.CTZ: Chemoreceptor trigger zone; GI: Gastrointestinal.Adapted from [30].