問題詳情

46.下列何者為warfarin代謝成7-hydroxywarfarin的最主要酵素？
(A)CYP1A4
(B)CYP2C9
(C)CYP3A4
(D)CYP1A2

參考答案

答案：B
難度：簡單0.761765
統計：A(3),B(259),C(65),D(13),E(0)

用户評論

【joker】評論

圖片來源:https://www.researchgate.net/figure/231223076_fig3_Metabolism-of-warfarin-Warfarin-an-enantiomeric-mixture-of-equal-concentrations-of-R

【焦糖瑪奇朵】評論

s-warfarin(活性)經過2C9 --6-hydroxywarfarin, 7-hydroxywarfarinR-warfarin 經過3A4 1A2 2C19-- 4'-hydroxywarfarin, 6-hydroxywarfarin, 8-hydroxywarfarin