問題詳情

67.下列何種抗黴菌藥物之作用機制是抑制真菌細胞壁glucan之合成？
(A)5-fluorocytosine
(B)voriconazole
(C)caspofungin
(D)nikkomycin Z

參考答案

答案：C
難度：適中0.666667
統計：A(0),B(1),C(4),D(1),E(0)

用户評論

【UiuUuuuu】評論

*5-fluorocytosine 抑制DNA RNA*voriconazole 是一種triazole類抗黴菌劑。Voriconazole的主要作用模式為抑制黴菌中由細胞色素P450所媒介的14α-lenosterol去甲基化作用，這是黴菌麥角脂醇之生物合成的必要步驟http://www.ktgh.com.tw/Medicament_tbDrug_Look.asp?CatID=65&ModuleType=Y&NewsID=1743&Ordid=20988*Nikkomycin Z is a uridine-based nucleoside-peptide antibiotic which inhibits fungal chitinbiosynthesis by inhibiting chitin synthase. It has a role as an antifungal agent. It derives from a uridine.https://pubchem.ncbi.nlm.nih.gov/compound/nikkomycin_z#section=Top*caspofungin葡聚糖 [glucan] 合...