問題詳情

66.下列何者為 nateglinide 之主要代謝物?
(A)


(B)


(C)


(D)

參考答案

答案:B
難度:困難0.35
書單:沒有書單,新增

用户評論

過過小藥師】評論

這是考古題!!!!(以為這種偏題不會那麼...

terminator812】評論

複習一下糖尿病的藥理...

洪峻澤】評論

附上Foye課本的圖...

激烈的小學姊】評論

Nateglinide is a phenylalanine analogue of meglitinide where the benzoic acid carboxylate group is transposed to the α-carbon of the N-ethyl side chain, creating the amino acid functionality. Nateglinide binds selectively to the SUR1 on β-cells and has a much lower affinity for cardiac and skeletal muscles. 63 It is a chiral molecule synthesized as the S( +)-isomer with traces of the R(-)-isomer as an impurity. The S( +)-isomer is 100-fold more potent than the R(-)-isomer. Nateglinide is a rapidly absorbed insulin secretagogue that has a mechanism of action similar to that of repaglinide, wi...