問題詳情

10. A 56-year-old man with cryptococcal meningitis is being treated with flucytosine and amphotericin
B. Flucytosine is metabolized to 5-flurouracil by fungal cells which inhibits DNA synthesis. The
selectivity of flucytosine is due to a lack of which enzyme in mammalian cells?
(A)Cytosine deaminase
(B)N-acetyltransferase
(C)Uracil phosphoribosyl transferase
(D)Thymidylate synthetase

參考答案

答案:99

統計:A:2,B:0,C:0,D:0,E:0

難度:計算中