34. Which of the following consideration for the use of adjuvants in the older persons is correct?
(A) amitriptyline has more anticholinergic adverse effects than second-generation tricyclicantidepressants (nortriptyline or desipramine)
(B) Serotonin and norepinephrine reuptake inhibitors (SNRIs) have fewer of these undesiredeffects from tricyclic antidepressants but a greater risk of drug interactions and elevation ofliver enzymes
(C) Antiepileptic drugs are first-line agents to treat neuropathic pain in older persons with labeledindications
(D) carbamazepine may be useful for neuropathic pain, but less ideal in older adults due to druginteractions, renal, liver, and hematologic toxicity
(E) all of the above are correct descriptions for adjuvants use in older persons