30.Which of the following statements is/are TRUE of supercoiling?
(A) The relaxed form of DNA is more stable and is therefore the preferred form in the cell.
(B) Most organisms maintain their DNA in a slightly overwound state in order to enhance strand separation
during transcription and replication.
(C) Overwound DNA is in the B form so relaxed DNA has less turns than B-form DNA.
(D) Most organisms maintain their DNA in a slightly underwound state in order to compact their DNA.
(E) The relaxed form of DNA can only be maintained if the DNA is a closed circle.