問題詳情

2 下述那一個藥物，對於中樞神經GABA A 受體最具有選擇性（selective agonist）？
(A)Muscimol
(B)Baclofen
(C)Strychnine
(D)Pirenzepine

參考答案

答案：A
難度：困難0.368421
統計：A(14),B(6),C(9),D(9),E(0)

用户評論

【蘇莉琄】評論

中樞神經GABA A 受體拮抗劑：Bicuculline、Picrotoxin

【YOLO】評論

Pirenzepine：M1選擇性拮抗劑

【더보이즈讓我中簽】評論

muscimol、isoguvacine是GABAA 的直接作用劑A number of compounds are known to directly activate the GABAA  receptor.Of these compounds, muscimol and isoguvacine are the most well-known.Unlike GABA which does not cross the blood-brain barrier, these agents do enter the CNS and display GABA-mimetic activity following peripheral administration.Baclofen:GABAB作用劑Strychnine:GLY拮抗劑Pirenzepine：M1選擇性拮抗劑