50. Hypoxia condition is a common microenvironment within tumor. Hypoxia mightattenuate mitochondrial activity resulting to increased production of lactate. Basedon your knowledge , which of the following statements can explain the mechanismcorrelated hypoxia condition and the production of lactate?
(A) Low ATP production might increase phosphofructokinase activity leading toincrease lactate production.
(B) Low ATP production promotes glycogen synthesis leading to inactivation ofglycolysis.
(C) High ATP production promotes the carboxylation of Pyruvate leading togluconeogenesis.
(D) High ATP production inactivates hexokinase leading to decreased ofglycolysis.
(E) None of the above.