4. You are a member of the health care team for a 57-year-old womnan in whom hormone replacement therapy (HRT) is beingconsidered for postmenopausal symptoms. Which one of the following statements is correct?
(A) Long-term systemic HRT use is linked to increased breast cancer risks. These risks could be eliminated completely afierHRT discontinuation.
(B) Risk varied among HRT types, with higher risks for combination estrogen-progestogen treatments and longer duration ofusc.
(C) Adjustment for personal characteristics, smoking, alcohol intake, comorbidities, family history, and other prescribed drugsabolished the observed associations.
(D) Increased risk for combined progestogens was highest for dydrogesterone and lowest for norethisterone