【用戶】王瑞賢

【年級】高一上

【評論內容】根據Foey's 7 th  p.793(D) Rilmenidine and moxonidine are both highly selective for the I1 receptor while having low affinity for a2-adrenoceptors, and both control blood pressure effectively without the adverse effects associated with binding to a2-receptors (e.g., sedation, bradycardia,and mental depression)(B)Clonidine appears to be more selective for a2 -adrenoceptors than for I1 receptors(A)Agmatine , an aminoguanidine, is an endogenous neurotransmitter found in the brain with high affinity for the G protein–coupled imidazoline receptors, I1 and I2, a2, and glutaminergic N-methyl-d-asp...

【用戶】如果詳解被鎖找 北醫王瑞賢

【年級】高一上

【評論內容】【解題】節錄自整理自7th Foey's p.793內文(A) agmatine對I1、I2、α2親和力都很高(B) clonidine對α2選擇性高於I1(D) Rilmenidineand moxonidine對I1選擇性高，但對α2選擇性低【延伸學習 & 國考複習】(完整表格詳見北醫藥學103級藥理藥化統整本 3.0 P42)【補充原文】根據Foey's 7 th  p.793(D) Rilmenidine and moxonidine are both highly selective for the I1 receptor while having low affinity for a2-adrenoceptors, and both control blood pressure effectively without the adverse effects associated with binding to a2-receptors (e.g., sedation, bradycardia,and mental depression)(B)Clonidine appears to be mor...