【過過小藥師】評論

統整樓上+自己的理解 化學性拮抗 化...

【shinju】評論

Profaning 為一鹼性帶正電之蛋白質，可中和酸性帶負電之肝素，而作為肝素(heparin)中毒之解毒劑。

【玩到腦中風】評論

我找了一篇BJA期刊，有興趣可以看看https://www.bjanaesthesia.org/article/S0007-0912(18)30061-8/fulltextProtamine is a highly positively charged peptide consisting of about 32 amino acids, and neutralises the effect of heparin through electrostatic binding between the cationic arginine groups of protamine and the anionic heparin in a 1:1 ratio. The resulting neutral protamine–heparin salt aggregates are clearly visible as white suspension and are formed within seconds. In parallel, the binding of protamine to heparin dissociates the anti-thrombin/heparin complex, leading to the recovery of the ...