【評論主題】6 α-Methyldopa 的降血壓作用主要是來自下列何種代謝物？(A)α-Methyldopamine (B)α-Methylepinephrine(C)α-Methylnorepinephrin

【評論內容】Methyldopa (L-α-Methyl-3,4-dihydroxyphenylalanine; Aldomet, Aldoril, Dopamet, Dopegyt, etc.) is a centrally acting antihypertensive agent. It is metabolized to alpha-methylnorepinephrine in the brain, and this compound is thought to activate central alpha-2 adrenergic receptors (Gerber, 1990).

【評論主題】下列藥物中，何者應避免在懷孕時使用？(A) Hydralazine(B) Methyldopa(C) Magnesium (D) Captopril

【評論內容】Angiotensin-converting enzyme (ACE) inhibitors have been widely used to control hypertension, but their use during gestation may result in fetal death, intra-uterine growth retardation, oligoamnium sequence, hypotension, acute renal failure and ductus arteriosus patency in the newborn.

【評論主題】下列藥物中，何者應避免在懷孕時使用？(A) Hydralazine(B) Methyldopa(C) Magnesium (D) Captopril

【評論內容】Angiotensin-converting enzyme (ACE) inhibitors have been widely used to control hypertension, but their use during gestation may result in fetal death, intra-uterine growth retardation, oligoamnium sequence, hypotension, acute renal failure and ductus arteriosus patency in the newborn.

【評論主題】6 α-Methyldopa 的降血壓作用主要是來自下列何種代謝物？(A)α-Methyldopamine (B)α-Methylepinephrine(C)α-Methylnorepinephrin

【評論內容】Methyldopa (L-α-Methyl-3,4-dihydroxyphenylalanine; Aldomet, Aldoril, Dopamet, Dopegyt, etc.) is a centrally acting antihypertensive agent. It is metabolized to alpha-methylnorepinephrine in the brain, and this compound is thought to activate central alpha-2 adrenergic receptors (Gerber, 1990).

【評論主題】下列藥物中，何者應避免在懷孕時使用？(A) Hydralazine(B) Methyldopa(C) Magnesium (D) Captopril

【評論內容】Angiotensin-converting enzyme (ACE) inhibitors have been widely used to control hypertension, but their use during gestation may result in fetal death, intra-uterine growth retardation, oligoamnium sequence, hypotension, acute renal failure and ductus arteriosus patency in the newborn.