【評論主題】70.下列那些抗黴菌的機制是抑制麥角醇(ergosterol)合成?①Polyene ②Azole ③Allylamine④Flucytosine(A)①②(B)②③(C)③④(D)①③

【評論內容】

polybrene作用在cell membrane sterols

allylamine作用在squalene epoxidase

flucytosine影響dna及rna合成

【評論主題】70.下列那些抗黴菌的機制是抑制麥角醇(ergosterol)合成?①Polyene ②Azole ③Allylamine④Flucytosine(A)①②(B)②③(C)③④(D)①③

【評論內容】

polybrene作用在cell membrane sterols

allylamine作用在squalene epoxidase

flucytosine影響dna及rna合成

【評論主題】45.下列何者為血栓溶解劑?(A)Tissue-type plasminogen activator(B)Thrombomodulin(C)Antithrombin III(D)Coumarin

【評論內容】

血栓溶解劑:streptokinase、urokinase、tPACoumarin為阻斷vitK還原作用,干擾凝血因子FactorⅡ、Ⅶ、Ⅸ、Ⅹ在肝臟中活化。

【評論主題】41 做干擾實驗時,下列何種病毒常作為挑戰病毒株(challenge virus)?(A)艾可病毒11型(echovirus 11)(B)麻疹病毒(measles virus)(C)第二型單純疱疹病毒

【評論內容】

Virus challenge studies:healthy volunteers are administered a pathogenic or virulent strain of virus.

Such strains can be attenuated viruses that produce a much milder set of symptoms compared to the naturally occurring or fully active virus.

【評論主題】70.下列那些抗黴菌的機制是抑制麥角醇(ergosterol)合成?①Polyene ②Azole ③Allylamine④Flucytosine(A)①②(B)②③(C)③④(D)①③

【評論內容】

polybrene作用在cell membrane sterols

allylamine作用在squalene epoxidase

flucytosine影響dna及rna合成

【評論主題】8.病人咽喉檢體在Tinsdale's agar上長出帶有棕色暈環(brown halo)之黑色菌落,此病人最可能感染下列何種病原菌?(A)Staphylococcus aureus(B)C

【評論內容】

含有potassium tellurite,Corynebacterium會還原tellurite回metallic tellurium,為棕色。