【評論主題】80 Cyclophosphamide 進入體內,在 pH 7.4 下,主要產生何物而烷化 DNA?(A)  (B)  (C)  (D)

【評論內容】Cyclophosphamide經過CY☆2☆6/3☆4★★★...

【評論主題】2 Suicide inhibitor 又稱為:(A) Transition-state inhibitor (B) Reversible enzyme inhibitor(C) Mechanism-

【評論內容】

▲ 酵素抑制劑依據Foye的分類可分為:

✔︎ 可逆型酵素抑制劑    1. Antimetabolites    2. Inhibition of HIV-RT    3. Reversible Inhibitor Used in Cancer Therapy    4. Inhibition of AchE    5. Inhibition of ACEI    6. Transition- State Inhibitor of Adenosine Deaminase✔︎ 不可逆型酵素抑制劑    1. Affinity Labels and Active Site Directed Irreversible Inhibitor    2. Mechanism Based Irreversible Enzyme Inhibitor

▲ 關於 Mechanism Based Irreversible Enzyme Inhibitor:

❶ 此類抑制劑又稱為Suicide substrate, Kcat inhibitors, Trojan horse inhibitor, Latent alkylating agent。❷ Subst...