【評論主題】46.下列何者最不建議用於治療neonatal seizures? (A)phenobarbital (B)valproic acid (C)phenytoin (D)lorazepam
【評論內容】
Valproic acid可能造成新生兒神經管缺陷
【評論主題】6.有關藥品與包裝標示之警語配對,下列何者最不適當? (A)verapamil-不可與葡萄柚汁併服 (B)famotidine-應空腹服用 (C)pseudoephedrine-避免在睡前服用 (D
【評論內容】(A) verapamil-不可與葡萄柚汁併服(B) famotidine-應空腹服用(C) pseudoephedrine-避免在睡前服用
有些藥物反而會影響睡眠,像支氣管擴張劑(theophylline)、緩解鼻塞的偽麻黃鹼(pseudoephedrine)等
Ref. 新北市藥師公會
(D) chlorpheniramine-服藥後,避免開車或操作危險機械CNS depression: May cause CNS depression, which may impair physical or mental abilities; patients must be cautioned about performing tasks which require mental alertness (eg, operating machinery or driving).
Ref. UptoDate
...【評論主題】24.有關抗癌藥品製備之敘述,下列何者正確? (A)cisplatin須以5% dextrose稀釋,因dextrose可減少腎毒性 (B)gemcitabine回溶後濃度須≦40 mg\\/mL,
【評論內容】(A) Cisplatin因為含Cl,故只能用NS稀釋
【評論主題】9.有關疫苗之儲存管理,下列敘述何者錯誤? (A)應使用專用冰箱或冷藏櫃且有溫度監控,每日至少查核記錄溫度兩次 (B)若溫度監視卡的D格顯示為藍色,即使目前儲存疫苗的冰箱溫度正常,此批疫苗也不可再用
【評論內容】(D)每天至少 2 次(上、下午)查核記錄冰箱之最高溫度、最低溫度、查核時溫度
【評論主題】2.下列何者可做為眼藥水之增稠劑(viscosity enhancer)? (A)chlorhexidine acetate (B)phenylmercuric nitrate (C)hyprome
【評論內容】
(A)chlorhexidine acetate →防腐劑preservatives
https://app.yamol.tw/item/1384198
(B)phenylmercuric nitrate →防腐劑preservatives
Long-term use of eye-drops containing phenylmercuric nitrate as a preservative
Ref. Meyler's Side Effects of Drugs (Sixteenth Edition), 2016
(C)Hypromellose→hydroxypropyl methylcellulose (HPMC)增稠劑
(D)chlorobutanol →防腐劑preservatives
【評論主題】4.有關raloxifene於骨鬆症治療之敘述,下列何者錯誤? (A)須考量靜脈栓塞病史 (B)依creatinine clearance調整劑量 (C)須注意與cholestyramine之交互作
【評論內容】(A) 須考量靜脈栓塞病史(B) 依creatinine clearance調整劑量(C) 須注意與cholestyramine之交互作用(D) 須考量肺栓塞之風險 [US Boxed Warning]: Raloxifene may increase the risk for deep vein thrombosis and pulmonary embolism (A)(D); use is contraindicated in patients with history of or current venous thromboembolic disorders Ref. UptoDateDosing: Kidney Impairment: AdultCrCl ≤50 mL/minute: There are no dosage adjustments (B) provided in the manufacturer’s labeling; use with caution. Ref. UptoDateConcurrent use of CHOLESTYRAMINE and RALOXIFENE may result in reduc...