【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】3 能改善長期洗腎患者低血鈣症狀的藥物：(A)α-Tocopherol(B)Isotrentinoin(C)Calcipotriene(D)Calcitriol

【評論內容】

(A) α-Tocopherol --> vit. E(B) Isotrentinoin -->A酸(C) Calcipotriene --> vit. D3(D) Calcitriol --> Vit D3類似物-->牛皮癬軟膏

【評論主題】45 以亞硫酸氫鈉法（bisulfite method）測定醛或酮的含量，必須控制溶液的 pH 值，下列何者不是使用酚酞的理由？(A)滴定終點的指示劑(B)判斷何時加入亞硫酸氫鈉的指示劑(C)判斷何時

【評論內容】

可以從選項敘述下手，B和C基本上是在敘述相同的事，所以先刪出。

假如B和C成立的話，D應該也會是對的。所以選A

【評論主題】45 以亞硫酸氫鈉法（bisulfite method）測定醛或酮的含量，必須控制溶液的 pH 值，下列何者不是使用酚酞的理由？(A)滴定終點的指示劑(B)判斷何時加入亞硫酸氫鈉的指示劑(C)判斷何時

【評論內容】

求解+1QQ

【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】24 下列有關(-)-Cocaine 敘述，何者錯誤？(A)其Tropine 架構具光學活性(B)水解產物之一為Benzoic acid(C)(-)-Cocaine 具有四個不對稱碳原子(D)萃取處理

【評論內容】

cocaine = ecgonine + methyl alcohol + benzoic acid 

【評論主題】19 下列有關Caffeine 生合成的敘述，何者錯誤？(A)第4 及5 位碳原子源自Glycine(B)第2 位碳原子源自CO 2(C)第1 位氮原子源自Aspartic acid(D)第3 及9

【評論內容】

45 Caffeine 的生合成與下列何種胺基酸無關？(A) Phenylalanine(B) Glycine(C) Serine(D) Glutamine .

【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】3 能改善長期洗腎患者低血鈣症狀的藥物：(A)α-Tocopherol(B)Isotrentinoin(C)Calcipotriene(D)Calcitriol

【評論內容】

(A) α-Tocopherol --> vit. E(B) Isotrentinoin -->A酸(C) Calcipotriene --> vit. D3(D) Calcitriol --> Vit D3類似物-->牛皮癬軟膏

【評論主題】45 以亞硫酸氫鈉法（bisulfite method）測定醛或酮的含量，必須控制溶液的 pH 值，下列何者不是使用酚酞的理由？(A)滴定終點的指示劑(B)判斷何時加入亞硫酸氫鈉的指示劑(C)判斷何時

【評論內容】

可以從選項敘述下手，B和C基本上是在敘述相同的事，所以先刪出。

假如B和C成立的話，D應該也會是對的。所以選A

【評論主題】45 以亞硫酸氫鈉法（bisulfite method）測定醛或酮的含量，必須控制溶液的 pH 值，下列何者不是使用酚酞的理由？(A)滴定終點的指示劑(B)判斷何時加入亞硫酸氫鈉的指示劑(C)判斷何時

【評論內容】

求解+1QQ

【評論主題】11 金雞納鹼（Quinine）的生合成源是：(A)Quinoline＋Quinuclidine(B)Tyrosine＋Tyrosine(C)Tryptophan＋Terpenoid(D)Tyrosi

【評論內容】

quinidine = quinuclidine + quinoline 

【評論主題】16.有關周邊靜脈營養溶液與 fat emulsion 同時輸注之敘述，下列何者錯誤？ (A)可降低 osmolarity (B)可緩衝 pH 值 (C)可改善周邊靜脈的耐受性 (D)可降低 thro

【評論內容】TPN加入Fat Emulsion可以減少靜脈炎和對靜脈的刺激，因為：1. Lower Osmolality: The addition of fat emulsion to TPN can decrease the overall osmolality of the TPN solution. Osmolality refers to the concentration of solutes in a solution, and solutions with higher osmolality can be more irritating to blood vessels and surrounding tissues. By lowering the osmolality, the fat emulsion can make the TPN solution less irritating to the veins, reducing the risk of phlebitis, which is inflammation of the vein.2. pH Stabilization: Fat emulsions contain phospholipids that can help stabilize the pH of the TP...

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】24 下列有關(-)-Cocaine 敘述，何者錯誤？(A)其Tropine 架構具光學活性(B)水解產物之一為Benzoic acid(C)(-)-Cocaine 具有四個不對稱碳原子(D)萃取處理

【評論內容】

cocaine = ecgonine + methyl alcohol + benzoic acid 

【評論主題】19 下列有關Caffeine 生合成的敘述，何者錯誤？(A)第4 及5 位碳原子源自Glycine(B)第2 位碳原子源自CO 2(C)第1 位氮原子源自Aspartic acid(D)第3 及9

【評論內容】

45 Caffeine 的生合成與下列何種胺基酸無關？(A) Phenylalanine(B) Glycine(C) Serine(D) Glutamine .

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】65 下列有關鋰鹽（lithium）之敘述何者正確？(A)其作用機轉主要為抑制 PI turnover 而降低細胞的興奮性(B)為急性躁期之首選藥物，但其作用仍需一週才有療效(C)會出現手抖之副作用，

【評論內容】

(A) 其作用機轉主要為抑制 PI turnover 而降低細胞的興奮性 (O)(B) 為急性躁期之首選藥物，但其作用仍需一週才有療效 (X) 

都是要治療急性了，還需要一週XD?(C) 會出現手抖之副作用，可以用β-agonist 減輕之

應該是β-blocker(D) 會出現水腫，與 potassium retention 有關 .

應該是sodium-retention  (Na在哪，水在哪)

【評論主題】75.下列各項敘述，何者正確？(A)Bornträger試劑可做為生物鹼之檢測試劑(B)Atropine即是(±)-scopolamine(C)Mescaline係由phenylalanine衍生而來

【評論內容】

yellow bark --> quinine

cuprea bark --> quinidine

red bark --> cinchonidine --> cinchona red

【評論主題】75.下列各項敘述，何者正確？(A)Bornträger試劑可做為生物鹼之檢測試劑(B)Atropine即是(±)-scopolamine(C)Mescaline係由phenylalanine衍生而來

【評論內容】

isoquinoline alkaloids

papaverine, tubocurarine, sanguinarine, hydrastine, photoberberines, emetine skeleton

四級胺: berberine, sanguinarine, tubocurarine

【評論主題】52.下列何者具有刺激性瀉下作用？(A)Myristic acid(B)Palmitic acid(C)Gallic acid(D)Ricinoleic acid

【評論內容】

caster oil --> 蓖麻油-->ricin, 術前清腸

【評論主題】6.以酸滴定分析法測定六次甲四胺（hexamine, methenamine）的含量時，可由下列那一試劑的顏色判斷六次甲四胺之分解已經完全？(A)過氯酸（perchloric acid）(B)硫酸鐵銨

【評論內容】

變色酸-->測甲醛--> hexamine hexamine 水解產生甲醛(可用臭味或是變色酸判定)

【評論主題】8.Vitamin E檢品溶液加入硝酸2毫升，於75 ℃加熱15分鐘，即呈現何種顏色？(A)白色至褐白色(B)亮紅色或橙色(C)深藍色(D)棕黑色

【評論內容】

☆☆☆ ☆

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics

【評論主題】62.下列有關「Wagner-Nelson Method」之敘述，何者正確？(A)可應用於二室模式排除速率常數之推估(B)利用藥物未吸收百分率對時間作圖，以求得吸收速率常數之法(C)應利用後段時間所得

【評論內容】Wagner-Nelson MethodAvailable forNON-1 order absorption and when ka is not 3 times larger than kelBUT you have toobtain the kel from IV data

【評論主題】6.下列對於「芳香水劑」特性之敘述，何者較不適當？(A)屬水溶液之製劑(B)通常含揮發性成分(C)芳香成分通常呈飽和狀態(D)樟腦水不宜使用於眼用製劑

【評論內容】

樟腦水-->有清涼感-->眼用或是洗劑

【評論主題】27.下列基劑何者最適合用來製備對水不安定的tetracycline 軟膏？(A)單軟膏(B)聚乙二醇軟膏(C)水油型軟膏基劑(D)油水型軟膏基劑

【評論內容】

補充個: 同樣有「單」字的單醣漿-->是蔗糖糖漿

【評論主題】25.下列何者之物理化學分類不屬於吸收性基劑（absorption base）？(A)消散乳霜（vanishing cream）(B)水基劑（aquabase）(C)羊毛脂（lanolin）(D)冷霜

【評論內容】

吸收性基劑-->很油

水和性--> 水可以洗掉

水溶性 --> 無油 (PEG)

【評論主題】70.Ibuprofen是屬於下列何者之衍生物？(A)N-Arylanthranilic acid(B)Arylbutyric acid(C)Salicylic acid(D)Arylpropioni

【評論內容】

Slicylic acid

Diflunisal

P-aminophenol, aniline derivatives

Acetaminophen

Arylacetic acid

Indomethacin, sulidac(-lac), diclofenac (-fenac)

Phenyl-α-propionicacid

-profens and naproxen

Enolic

-oxicams (meloxicam 有thiazole)

N-arylanthranilic acid

Mefenamic acid

Propionic acid

【評論主題】54.Leu-enkephalin是由幾種不同的胺基酸組成？(A)3(B)4(C)5(D)6

【評論內容】Endomorphin 1:tyrosine-proline-tryptophan-phenylalanine

【評論主題】71 下列何種治療微生物感染的製劑，對於腎功能不佳的病人需要調低劑量？(A)chloramphenicol(B)erythromycin(C)metronidazole(D)acyclovir

【評論內容】腎臟: cephalosporin,penicillins, vancomycin, most tetracycline (except doxycycline), mostFQ(except for moxifloxacin)肝臟: chloramphenical(link--> gray baby syndrome), doxycylcine, moxyfloxacine

【評論主題】42 那一種鈉管道抑制劑作用與 Lidocaine 相似，但常用於糖尿病人神經病變後之疼痛（neuropathic pain）？(A) Quinidine (B) Mexiletine (C) Fle

【評論內容】

Mexiletine, Lidocaine, phenytoin 都是class Ib 的 inactive Na+ channel blocker

【評論主題】27 下列何藥用於治療便秘及肝臟疾病引起之腦病變？(A) Castor oil (B) Lactulose (C) Mineral oil (D) Sorbitol

【評論內容】

想要請問為什麼不能選sorbitol?

【評論主題】21 那一種利尿劑較會增加靜脈血管之容積（Venous capacitance），而減輕肺水腫之症狀？(A) Amiloride (B) Bumetanide (C) Acetazolamide (D

【評論內容】

furosemide, spino☆☆☆☆☆☆☆☆☆ --&...

【評論主題】56 下列鴉片類止痛劑（opioid analgesics），何者具有 anilidopiperidines 的骨架？(A) Fentanyl (B) Buprenorphine (C) Butorp

【評論內容】

Anilidopiperidine

Fentanyls

4-phenylpiperidine

Meperidine

【評論主題】23 下列那一種降壓藥物最易引起鹽類與水分在體內蓄積？(A) Nicardipine (B) Timolol (C) Irbesartan (D) Diazoxide

【評論內容】

Diazoxide為一thiazide結構物，但缺乏利尿作用。會使鉀離子通道開啟，造成過極化，可用於高血壓。

【評論主題】73 下列何者具有   之結構？(A) Promethazine (B) Pyrrobutamine (C) Phenindamine (D) Chlorcyclizine

【評論內容】

題目的結構-->pyrrolidine

【評論主題】30.下列那一種抗憂鬱藥物﹐其產生直立性低血壓（Orthostatic hypotension）的副作用最強？(A)Fluoxetine(B)Phenelzine(C)Amitriptyline(D)

【評論內容】

Phenelzine (Nardil, Nardelzine) is a non-selective and irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class which is used as an antidepressant and anxiolytic

【評論主題】22 於栓劑基劑 Wecobee 中加入下列何種物質可增加栓劑的含水量？(A) Aspirin (B) Chloral hydrate(C) Glycerol monostearate (D) Ste

【評論內容】可可脂若含有phenol 或是chloral hydrate(兒童常用鎮靜安眠藥)，會導致熔點下降-->加硬化劑鯨蠟、beeswax or aluminium stearate

【評論主題】63 下列有關氣相層析儀之敘述，何者錯誤？(A)毛細管柱比填充管柱的樣品承載量低(B)氣相層析之衍生化需用到後置衍生裝置(C)聚乙二醇（Carbowax 20M）管柱適合極性分析物的分析(D)攜帶氣體

【評論內容】

Carbowax = PEG--> 極性大

【評論主題】13 下列有關乳劑乾膠法之敘述，何者錯誤？(A)油：水：Acacia 可為 40 mL：20 mL：10 g (B)宜用玻璃乳鉢(C)先形成初乳（primary emulsion） (D)又稱為大陸法

【評論內容】Internal phase to externalphase ( Wet gum, English, American) [O/W]H2O + acacia緩慢加入內相(oil)同方向攪拌直到初乳形成Diluted with H2O to finalvolumeExternal to internal phase(Dry gum, continental method) Oil + acacia+H2O all at once攪拌 ---->crackling soundDiluted with water to finalvolume

【評論主題】60 某藥物屬於線性模式藥物動力學，靜脈注射時給與二倍的劑量，則下列敘述何者正確？(A)藥物的半衰期將降低一半 (B)藥物的分布體積將降低一半(C)藥物的清除速率將增加一倍 (D)藥物的曲線下面積將增

【評論內容】

增加一倍，就是原本的AUC*2的意思QQ

【評論主題】80 醫藥用之 ergot alkaloids，含有下列那種主要的組成單位？(A)(+)-lysergic acid (B)(+)-isolysergic acid (C)(-)-lysergic a

【評論內容】Most alkaloids in ergot category are derivatives of (+)-lysergicacid---> (+)-isolysergic acid (physiologically inert) --->-in- in the name

【評論主題】77 於 yellow cinchona 之黃樹皮中，其所含有之生物鹼主要為：(A) Quinine (B) Quinidine (C) Cinchonine (D) Cinchonidine

【評論內容】Yellow bark--> quinine(1/2~2/3); Red bark: cinchonidineIn red bark(cinchonidine)-->cinchotannic acid--> insoluble cinchona red

【評論主題】73 下列何種生物鹼其化學性質與另三者有極大的差異？(A) Hydrastine (B) Tubocurarine (C) Berberine (D) Sanguinarine

【評論內容】Phthalideisoquinolines(γ-lactone ring):hydrastine

【評論主題】59 下列有關 nutmeg oil 之敘述，何者錯誤？(A)以水蒸氣蒸餾法萃取 (B)藥用部位為 Myristica fragrans 的成熟種子(C)所含 terpenoids 主要為 sesqu

【評論內容】

nutmeg --> volatile oil --> myristicin -->迷幻作用

【評論主題】21 苯胺（Aniline）溶於 HCl 溶液中，會發生最大吸光波長之改變，此乃因發生：(A) Bathochromic shift (B) Hypsochromic shift (C) Hypoch

【評論內容】

若苯的對稱性因取代基而減少，光譜會進行深色移動(bathochromic shift) -->移到較常波長處

Phenol or aniline + base --> bathochromic and hyperchromic shift

【評論主題】6 利用沈澱殘餘滴定法，對氯化鈉進行含量測定時，加入硝酸的目的，不包括下列何者？(A)防止碳酸銀沈澱物之生成 (B)防止鐵明礬（Ferric alum）水解(C)防止磷酸銀沈澱物之生成 (D)防止硫氰

【評論內容】

(D)硫氰酸銨是反滴定液

【評論主題】12 下列有關螢光光度測定法的敘述，何者錯誤？(A)溶液溫度會影響測定值(B)比紫外光光度法的靈敏度高(C)極易受檢品中灰塵及其他微小粒子的影響(D)有機螢光物質的螢光激發狀態的持續時間比磷光者為長

【評論內容】

Half life: phos. > fluo>absorb.

【評論主題】18 依下列反應式，KIO 3 濃度 0.05 M 相當於多少 N？2KI＋KIO 3＋6HCl → 3ICl＋3KCl＋3H 2 O(A) 0.05 (B) 0.1 (C) 0.2 (D) 0.3

【評論內容】

想要請問樓上~應該不是看K而是看I吧?

【評論主題】50 Lobeline 屬於下列何者之衍生物？(A)Pyridine(B)Piperidine(C)Pyrrolidine(D)Quinoline

【評論內容】

piperidine: lobeline

nicotinic acid: arecoline

pyridine and pyrrolidine: nicotine 

lobeline from Lobelia 北美山梗菜 --> emetics