問題詳情

65 下列屬於 Triptans 類之藥品中,何者與 CYP3A4 抑制劑具有最顯著之交互作用,應避免合併使用?
(A) Eletriptan
(B) Rizatriptan
(C) Zolmitriptan
(D) Frovatriptan

參考答案

答案:A
難度:困難0.295931
統計:A(240),B(151),C(129),D(44),E(0)

用户評論

【用戶】海星

【年級】高一下

【評論內容】(A) Eletriptan:3A4 排除(B) Rizatriptan:MAO-A 排除(C) Zolmitriptan:MAO-A , 1A2 排除(D) Frovatriptan:1A2 排除

【用戶】Jumpjump

【年級】高三上

【評論內容】Sumatriptan 經MAO-A代謝、不經過CYP450

【用戶】海星

【年級】高一下

【評論內容】(A) Eletriptan:3A4 排除(B) Rizatriptan:MAO-A 排除(C) .....看完整詳解

【用戶】Jumpjump

【年級】高三上

【評論內容】Sumatriptan 經MAO-A代謝、不經過CYP450

【用戶】炸雞翅

【年級】大一上

【評論內容】記:Eletriptan 的E像是★★★★...

【用戶】Tegralition

【年級】

【評論內容】Inhibitors of cytochrome P-450 (CYP) 3A4 reduce the clearance of almotriptan and eletriptan. For almotriptan, increased exposure to triptans should be anticipated; however, no specific dosing adjustments are proposed. The interaction between eletriptan and CYP 3A4 inhibitors is more significant, and particular precautions are necessary. Eletriptan should not be used within 72 hours of treatment with potent CYP 3A4 inhibitors (e.g., ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, and nelfinavir).Applied 10e p134...