用戶【Tegralition】點評問題和點評內容

【評論主題】31.下列何者較不會引起次發性高血壓?(A)tacrolimus (B)sacubitril (C)sorafenib (D)sunitinib

【評論內容】applied 11e p136applied 11e p1990

【評論主題】65 下列屬於 Triptans 類之藥品中,何者與 CYP3A4 抑制劑具有最顯著之交互作用,應避免合併使用?(A) Eletriptan (B) Rizatriptan (C) Zolmitrip

【評論內容】Inhibitors of cytochrome P-450 (CYP) 3A4 reduce the clearance of almotriptan and eletriptan. For almotriptan, increased exposure to triptans should be anticipated; however, no specific dosing adjustments are proposed. The interaction between eletriptan and CYP 3A4 inhibitors is more significant, and particular precautions are necessary. Eletriptan should not be used within 72 hours of treatment with potent CYP 3A4 inhibitors (e.g., ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin, ritonavir, and nelfinavir).Applied 10e p134...