【Swear】評論

Adefovir由腎小管分泌排除，腎功能不佳者，須注意其Scr之變化，高劑量之Adefovir投與後，會造成病患Scr升高。

【Bryan】評論

Adefovir is a prescription medicine used to treat infections with hepatitis B virus.Adefovir Dipivoxil Tablets are indicated for the treatment of chronic hepatitis B in patients 12 years of age and older with evidence of active viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.This indication is based on histological, virological, biochemical, and serological responses in adult patients with HBeAg+ and HBeAg- chronic hepatitis B with compensated liver function, and with clinical evidence of lamivudine-resista...

【草薙素子】評論

(A) Adefovir 有腎毒害的副作用，所以需要測 Scr。一般來說，肝炎藥物為了要保護腎臟，排除途經多避開肝而經由腎，所以多有腎毒性。(B) HBeAg：B肝病毒活動性、複製能力（感染性）的指標。(C) ALT/AST：監測肝功能，看用藥後是否有確實降低。(D) LDH↑只代表體內有組織損傷。

【YUI_1222】評論

乳酸中毒副作用，肝功能不好者容易發生Zidovudine,stavudine