33. Which of the following features are correct regarding the mechanism of DNApolymerase?
(A) DNA polymerase uses a single active site to catalyze the addition of any of thefour deoxynucleoside triphosphates.
(B) Steric constraints prevent DNA polymerase from using ribonucleosidetriphosphates as substrate.
(C) The thumb domain of DNA polymerase is intimately involved in catalysis.
(D) Processivity is a crucial character for DNA polymerase and defines the averagenumber of nucleotides added per template binding event.
(E) Removal of incorrectly base-paired nucleotides is mediated by intrinsicendonuclease activity of DNA polymerase.