31.Which one of the following statements is wrong?
(A) Pain and hyperalgesia arise in part from the action of inflammatory mediators on theperipheral terminals of nociceptive neurons.
(B) The list of inflammatory mediators may include arachidonic acid metabolites, bradykinin,adenosine triphosphate and nitric oxide.
(C) A series of inflammatory cytokines and chemokines, such as tumor necrosis factor-α andinterleukin-1β, and growth factors, particularly nerve growth factor, are capable of changingthe response properties of pain-signaling neurons.
(D) The inflammatory mediators may activate nociceptive terminals or regulate gene expression ofnociceptors.
(E) All of the above are correct.