問題詳情

28.有關digoxin之敘述,下列何者正確?

(A)屬rhythm control抗心律不整藥品
(B)靜脈注射5~10分鐘可發揮抗心律不整作用
(C)腎衰竭病人速效劑量與維持劑量都要降低
(D)依據心律調整劑量,不須監測血中濃度

參考答案

答案:C

統計:A:163,B:124,C:640,D:5,E:0

難度:簡單

用户評論

terminator812】評論

(A) 屬rhythm control抗心律不整藥品

洪峻澤】評論

補充digoxin其他考點:digoxin中毒(作用增加)最容易引起心律不整 (心搏過緩、心臟傳導阻礙、心房顫動甚至心室頻脈)危險因子:低血鎂、低血鉀、高血鈣

IG:Pharmabook】評論

10th koda & kimble applied p.497(A) 選項應改成屬rhythm control抗心律不整藥品→ Rate control(B) IV注射後至少2小時可發揮抗心律不整作用,6-8小時後最大After an intravenous (IV) dose, digoxin will take more than 2 hours for the onset of effect and 6 to 8 hours for the maximal effect, which is markedly slower than other negative dromotropic agents(C)腎衰竭病人速效劑量與維持劑量都要降低If he had significant renal dysfunction, both the loading and the maintenance doses of digoxinwould need to be altered(D)需依照腎功能調整劑量,需進行TDM,對腎衰竭的治療濃度0.5 to 1.0 ng/mL