問題詳情

23.Leukocyte adhesion deficiency-I 起因於下列何種蛋白質的基因缺陷?

(A)Neutrophil elastase
(B)Lamin B receptor
(C)β2-integrin
(D)NADPH oxidase

參考答案

答案:C

統計:A:134,B:98,C:455,D:107,E:0

難度:適中

用户評論

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" β2 integrins are heterodimeric surface receptors composed of a variable α (CD11a-CD11d) and a constant β (CD18) subunit and are specifically expressed by leukocytes. The α subunit defines the individual functional properties of the corresponding β2 integrin, but all β2 integrins show functional overlap. They mediate adhesion to other cells and to components of the extracellular matrix (ECM), orchestrate uptake of extracellular material like complement-opsonized pathogens, control cytoskeletal organization, and modulate cell signaling. "           " LAD-I (leuko...

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白血球黏附缺陷(leukocyte adhesion deficiency)是因下列何類細胞黏附因子的common β chain缺失所致?