【用戶】滴水之恩湧泉以報
【年級】大一上
【評論內容】33.以層析法進行糖化血色素(HbA1c)分析測定時,選用何種固定相較適宜?(A)ODS(B)Borate gel(C)Silica gel(D)Alumina .編輯私有筆記及自訂標籤
【用戶】IKEA 鯊魚
【年級】高三下
【評論內容】(B) Borate gels 課本敘述 1. immobilised alkyl boronic acids.2. selective affinity for 1,2- or 1,3-diol groupings ( catechol-containing molecules=dopamine、sugars、glycosides)3. The analyte is loaded onto the gel in a buffer at ca pH 7.0 4. The complex formed can be broken down using a mildly acidic eluent such as 0.1 M acetic acid.5. Applied to the determination of dopamine, adrenaline and noradrenaline in plasma and to the determination of the extent of reaction of glucose with serum albumin as a measure of glucose fluctuations with time in diabetics33.以...
【用戶】所得皆所愿
【年級】大三上
【評論內容】Solid Phase Extraction SPE 固相萃取法親脂性矽膠利用Van der Waals滯留非極性藥物例子:固醇類陰離子交換樹脂弱酸性藥物(Methicillin)以陰離子萃取後,再以緩衝液沖提易被取代的沖提離子:OH-、C2H5COO-、CH3COO-、F-修飾矽膠表面(極性↑)表面修飾成aminopropyl / diol的形式滯留極性基團陽離子交換樹脂弱鹼性藥物(Adrenaline)以陽離子萃取後,再以緩衝液沖提易被取代的沖提離子:K+、Na+、NH4+正相吸附劑滯留極性基團沖提液:Ethanol/Methylene chloride硼酸膠體(Borate gels)能與Dopamine的catechol基團、醣類、配糖體錯合可用於血液中的Adrenaline、也可測糖尿病患者葡萄糖/白蛋白的反應程...