問題詳情

50 下列那一項藥品不會增加毛地黃中毒的危險?
(A)Cholestyramine
(B)Clarithromycin
(C)Spironolactone
(D)Furosemide

參考答案

答案:A
難度:適中0.5
統計:A(11),B(1),C(9),D(0),E(0)

用户評論

aaa】評論

Cholestyramine 會吸附其他藥品造成其他藥品藥效下降故在服用前1小時或服用後4小時避免和其他藥併用。

冰魚王】評論

有人知道為啥C不能選嗎低血鉀、低血鎂及高血鈣會加強digoxin的藥效反應,甚至導致中毒現象我就選了個保鉀..Interactions between your drugsMinordigoxin spironolactoneApplies to: digoxin, spironolactoneSpironolactonemay reduce the tubular secretion of digoxin. Plasma clearance ofdigoxin may be decreased, and plasma levels may increase. Also, limiteddata indicate that spironolactone may have a negative inotropic sideeffect. Finally, spironolactone may interfere with some digoxinradioimmunoassays, and digoxin concentrations may be overestimated.During coadministration, the patient should...

獨角仙女】評論

回樓上,我是這樣想雖然低血鉀會加重digoxin中毒的現象,但digoxin本身機轉應該是造成血鉀上升,再使用個保鉀利尿劑就更容易高血鉀,一樣會有心律不整的風險而且你上面也寫到Spironolactone may reduce the tubular secretion of digoxin. During coadministration, the patient should be monitored for signs and symptoms of digoxin toxicity,所以我覺得還是選A比較合理