【Bryan】評論

Milrinone is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.Milrinone is used as a short-term treatment for treat life-threatening heart failure.    Inotropic agent

【Bryan】評論

Inotropic agents affect the contraction of the heart muscle. Positive inotropes stimulate and increase the strength of heart muscle contraction causing the heart rate to increase. Negative inotropic agents weaken the force of muscular contractions.Inotropic state depends on the amount of calcium in the cytoplasm of the heart muscle wall, as contractility of the heart depends on control of intracellular calcium i.e. control of calcium entry into the cell membrane and calcium storage in the sarcoplasmic reticulum. The main factors controlling calcium entry are activity of voltage gated calcium c...

【Gina】評論

Milrinone為PDE3抑制劑。會增加細胞內cAMP的濃度，造成細胞內Ca2+增加，心臟收縮力增強。

【Gina】評論

Milrinone為PDE3抑制劑。會增加細胞內cA.....看完整詳解

【Bryan】評論

Milrinone is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries.Milrinone is used as a short-term treatment for treat life-threatening heart failure.    Inotropic agent

【Bryan】評論

Inotropic agents affect the contraction of the heart muscle. Positive inotropes stimulate and increase the strength of heart muscle contraction causing the heart rate to increase. Negative inotropic agents weaken the force of muscular contractions.Inotropic state depends on the amount of calcium in the cytoplasm of the heart muscle wall, as contractility of the heart depends on control of intracellular calcium i.e. control of calcium entry into the cell membrane and calcium storage in the sarcoplasmic reticulum. The main factors controlling calcium entry are activity of voltage gated calcium c...