【用戶】濃湯
【年級】大二下
【評論內容】抑制細胞壁Echinocandins:抑制葡聚醣Nikkomycin:抑制幾丁子抑制細胞膜Polyene與麥角固醇結合破壞通透imidazole/ketoconazole-cytochrome P450抑制抑制蛋白質cycloheximide:抑制轉錄抑制細胞核 griseofulvin阻止紡錘絲的形成,抑制真菌的有絲分裂抑制DNA、RNA5-Fluorocytosin抑制thymidylate synthetase,干擾黴菌DNA合成
【用戶】7you
【年級】國一下
【評論內容】Cycloheximide is a naturally occurring fungicide produced by the bacterium Streptomyces griseus. Cycloheximide exerts its effects by interfering with the translocation step in protein synthesis (movement of two tRNA molecules and mRNA in relation to the ribosome), thus blocking eukaryotic translational elongation from wiki抗真菌製劑機制圖表抗表皮真菌劑https://www.semanticscholar.org/paper/Antifungal-drugs-and-resistance%3A-Current-concepts-Nigam/1f2abff9c5b3b969cdda22ae23f2a85042ae7739所有抗真菌製劑https://www.researchgate.net/figure/Common-antifungal-drugs-in-the-market-and-their-cellular-targets_tbl1_5373934