問題詳情

61.有關colchicine的敘述，下列何者正確？
(A)與acidifying agent併用會加強colchicine之作用
(B)與atorvastatin併用會增加橫紋肌溶解症之發生率
(C)與fluconazole併用可能會降低colchicine的血中濃度
(D)僅適用於痛風急性發作治療

參考答案

答案：B
難度：適中0.452055
統計：A(6),B(33),C(6),D(28),E(0)

用户評論

【donna】評論

Colchicine交互作用：CNS depressants :Colchicine may increase sensitivity to the action of CNS depressants. Monitor the patient and adjust the CNS depressant dosage as needed. 減弱colchicine作用增強colchicine作用Acidifying agents :The action of colchicine is inhibited by acidifying agents. Avoid coadministration. 1.Alkalinizing agents:The action of colchicine is potentiated by alkalinizing agents. Avoid coadministration. 2.Grapefruit juice ：Colchicine plasma concentrations may be elevated by grapefruit juice ingestion, increasing the risk of toxicity (eg, myopathy). Advise patients taking...

【我要減肥!!】評論

也可用於Familial Mediterranean fever(家族性地中海熱 )

【pop100】評論

補充口服:0.5~0.6mg/Q1-2H至疼痛緩解或腹瀉(總劑量不可超過8mg)如不能口服改IV，但骨髓抑制毒性高