問題詳情

5.Sickle cell disease是由於β鏈第6個位置的麩胺酸(glutamic acid)被下列何種胺基酸取代?
(A)甘胺酸(glycine)
(B)離胺酸(lysine)
(C)酪胺酸(tyrosine)
(D)纈胺酸(valine)

參考答案

答案:D
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用户評論

Hsieh Guei YU】評論

Sickle cell anemia results from the single amino acid substitution of valine for glutamic acid in the beta-chain owing to a nucleotide defect that causes the production of abnormal beta-chains in hemoglobin S. Abnormal hemoglobin chains form polymers in the deoxygenated state, leading to the characteristic sickle cells. The polymerization of deoxygenated hemoglobin S accounts for the pathologic changes in sickle cell disease. The main-stay of therapy in sickle cell disease aims to reduce the amount of sickled hemoglobin present through the prevention of polymerization and reversal of this proc...

珍珠奶茶微冰微糖】評論

(B)離胺酸(lysine):HbC

我是醫檢師】評論

類似題Hb C disease是由於β球蛋白鏈上的麩胺酸(glutamic acid)被下列何種胺基酸取代?(1051)(A)甘胺酸(glycine)(B)離胺酸(lysine)(C)酪胺酸(tyrosine)(D)纈胺酸(valine)β球蛋白鏈上的麩胺酸(glutamicacid)被取代-->HbS  6  Val-->HbC  6   Lys:  易形成結晶-->HbE  26  Lys:  東南亞最常見63.下列何者為東南亞地區最常見的變異血紅素?(1101)(A)Hb C(B)Hb D(C)Hb E(D)Hb SC

@@@】評論

鐮刀型貧血(隱性遺傳)控制的基因★★★★★...

濃湯】評論

Hb s:Glu-valHb c:Glu-LysHb e:東南亞常見