【用戶】Aka.翻車大王
【年級】大二下
【評論內容】sulfa系列容易經acetyltransferase導致脂溶性、水溶性下降產生結晶尿除sulfadoxine 水溶性上升（真的是例外中的例外 所有藥物原本經acetyltransferase、methylation都不會增加極性）
【用戶】鋼槍小企鵝
【年級】大一下
【評論內容】sulfamethoxazole 在原文書還是列為 易結晶喔!原文書原文Sulfonamides may precipitate in urine, especially at neutral or acid pH, producing crystalluria, hematuria, or even obstruction. This is rarely a problem with the more soluble sulfonamides (eg, sulfisoxa-zole). Sulfadiazine and sulfamethoxazole are relatively insoluble in acidic urine and can cause crystalluria, particularly when given in large doses or if fluid intake is poor.