問題詳情

【題組】48.下列抗微生物製劑中,何者最不易穿透血腦障壁(blood-brain barrier)進入腦脊液?
(A)Imipenem/cilastatin
(B)Isoniazid
(C)Amphotericin B
(D)Vancomycin

參考答案

答案:C
難度:適中0.404641
統計:A(92),B(106),C(558),D(368),E(0)

用户評論

Jason Chen】評論

(A)Imipenem/cilastatin → 有腦膜炎時,易穿透BBB(B)Isoniazid → 沒有腦膜炎時,易穿透BBB(C)Amphotericin B → 有or沒有腦膜炎時,不易穿透BBB(D)Vancomycin → 有腦膜炎時,易穿透BBB

Bryan】評論

Isoniazid (Laniazid, Nydrazid), also known as isonicotinylhydrazine (INH), is an organic compound that is the first-line medication in prevention and treatment of tuberculosis.Amphotericin B (Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec) is a polyene antifungal drug, often used intravenously for systemic fungal infections.

加油】評論

1.下列何種治療不適用於隱球菌(Cryptococcus neoformans)引起的腦膜炎? (A)併用amphotericin B 0.5 mg/kg/day IV及flucytosine 100 mg/kg/day (B)Liposomal amphotericin B 4 mg/kg/day IV (C)Micafungin 150 mg qd IV (D)併用fluconazole 400 mg/day及amphotericin B 0.7 mg/kg/day 專技 - 藥物治療學- 103 年 - 103年第二次專技高考藥物治療學更正#17189