問題詳情

14 Theophylline 與下列何藥品併用時，會使 theophylline 代謝增加、血中濃度下降？
(A) Carbamazepine
(B) Ticlopidine
(C) Clarithromycin
(D) Enoxacin

參考答案

答案：A
難度：簡單0.887755
統計：A(261),B(6),C(24),D(3),E(0)

用户評論

【Bryan】評論

Carbamazepine may decrease theophylline serum levels. Also, theophyllines may decrease serum levels and effects of carbamazepine. The mechanisms may be related to induction of hepatic CYP450 metabolism.

【Bryan】評論

Carbamazepine may decrease theophylline serum levels. Also, theophyllines may decrease serum levels and effects of carbamazepine. The mechanisms may be related to induction of hepatic CYP450 metabolism.

【祝好運！一切順利~】評論

↓ theophylline 代謝↑☄   Cimetidine☄ Macrolides: Clarithromycin,  Erythromycin☄ Quinolones:  Ciprofloxacin☄  競爭CYP3A4代謝ticlopidine☄   脂肪/ 糖類食物☄   年紀 (<6 mos, 老人)☄   左心室衰竭. 肝功能異常.肺炎☄   Phenotoin☄   Phenobarbital☄   RIF☄   Smoking (為CYP1A2誘導劑)☄  抗癲癇藥☄  抗結核藥