問題詳情

73.周女士61歲，無任何慢性疾病，一個月前發現乳房異常腫塊，粗針抽吸檢查結果顯示：left breast，infiltrating ductal carcinoma，ER/PR negative，HER2/neu overexpression 3+，nuclear grade 3。此病人可以使用下列何種藥品治療？
(A)Tamoxifen
(B)Letrozole
(C)Trastuzumab
(D)Leuprolide

參考答案

答案：C
難度：簡單0.773279
統計：A(98),B(3),C(573),D(2),E(0)

用户評論

【Swear】評論

ER/PR negative: 動情激素接受體(ER)、黃體激素接受體(PR) negative，表明使用荷爾蒙拮抗劑效果不佳。

【花】評論

55.周女士61歲，無任何慢性疾病，病理報告顯示：ER/PR negative，HER2/neu overexpression3+，nuclear grade 3，診斷為infiltrating ductal carcinoma第二期，經過手術 切除，有關後續治療的選擇，下列何者錯誤？ (A)Doxorubicin + trastuzumab (B)Doxorubicin + cyclophosphamide (C)Docetaxel + trastuzumab (D)Docetaxel + cyclophosphamide

【毛茛葛格】評論

Trastuzumab女生看到糖，心臟就很挫怕得乳癌作用目標:HER2 (女生)不可用D5W稀釋 (糖)副作用:CHF、心毒性 Trastuzumab  Tra(挫)適應症:乳癌補充單株抗體 未立即使用須冷藏有效28天內

【疫情退散!!】評論

1.ER/PR negative: ★★★★★★★(☆☆)、...

【粗暴言論duck不必】評論

Leuprolide機轉Leuprolide is an agonist of gonadotropin releasing hormone (GnRH) receptors. Acting as a potent inhibitor of gonadotropin secretion, leuprolide produces an initial increase in luteinizing hormone (LH) and follicle stimulating hormone (FSH), which leads to a transient increase (5 to 12 days) in testosterone and dihydrotestosterone (in males) and estrone and estradione (in premenopausal females). Continuous leuprolide administration then results in suppression of ovarian and testicular steroidogenesis due to decreased levels of LH and FSH with subsequent decrease in testosterone (m...