問題詳情

70 李先生長期服用 phenelzine 治療精神疾患，因自行服用含 ephedrine 之感冒藥，導致頭痛、血壓上升。此現象極有可能是兩藥品間之何種作用造成的？
(A) Phenelzine 增加 ephedrine 的生體可用率
(B) Phenelzine 與 ephedrine 競爭相同蛋白結合位置
(C) Phenelzine 抑制 ephedrine 的代謝
(D) Phenelzine 與 ephedrine 競爭從泌尿道之排除

參考答案

答案：C
難度：適中0.521739
統計：A(7),B(31),C(84),D(4),E(0)

用户評論

【Bryan】評論

MAO inhibitorsIsocarboxazidPhenelzine (Nardil)Selegiline (Eldepryland others)Tranylcypromine (Parnate)Sympathomimetics:DopamineEphedrineIsometheptene mucateMephentermineMetaraminolPhenylephrinePseudoephedrineIncreased risk of hypertensive crisis due to increased norephinephrine availabilityAvoid combination therapyIf combination therapy is required, monitor blood pressure and for frequent headaches or palpitationsIf hypertensive crisis occurs, discontinue MAO inhibitor therapy and administer phentolamine 5 mg slow intravenous push to lower blood pressur...