【如果詳解被鎖找 北醫王瑞賢】評論
【解題】節錄自7th Foey's p.681內文buprenorphine has only partial mu agonist action, it will precipitate withdrawal in patients dependent on full mu agonists , but itnalso suppresses symptoms of full-blown withdrawal【延伸學習 & 國考複習】 (完整表格詳見北醫藥學103級藥理藥化統整本 3.0 P104)【整理自7th Foey's p.681內文】(底線部分為國考考過考點)(From 王瑞賢 1081藥理藥化詳解p.85)【Buprenorphine】需IV/舌下1.機轉： Partial μ agonist、κ partial antagonist2.高μ親和力：(1)原因：A.C7可結合H、OH B.高親脂性(2) pseudoirreversible：半衰期長(37hr)→可QD(3)可減緩戒斷症狀：因高親和力使其從μ受體降解速...