【用戶】Bryan

【年級】國三上

【評論內容】Flurazepam hydrochloride is rapidly absorbed from the G.I. tract. Flurazepam is rapidly metabolized and is excreted primarily in the urine. Following a single oral dose, peak Flurazepam plasma concentrations ranging from 0.5 to 4.0 ng/mL occur at 30 to 60 minutes post-dosing. The harmonic mean apparent half-life of Flurazepam is 2.3 hours.

【用戶】Bryan

【年級】國三上

【評論內容】Oxazepam, is a short-to-intermediate-acting 3-hydroxy benzodiazepine derivative.

【用戶】Bryan

【年級】國三上

【評論內容】Flurazepam hydrochloride is rapidly absorbed from the G.I. tract. Flurazepam is rapidly metabolized and is excreted primarily in the urine. Following a single oral dose, peak Flurazepam plasma concentrations ranging from 0.5 to 4.0 ng/mL occur at 30 to 60 minutes post-dosing. The harmonic mean apparent half-life of Flurazepam is 2.3 hours.

【用戶】Bryan

【年級】國三上

【評論內容】Oxazepam, is a short-to-intermediate-acting 3-hydroxy benzodiazepine derivative.

【用戶】小藥渣(111-1新手藥師

【年級】大四上

【評論內容】補個路徑這題當下看到A、B兩個選頂可以先刪掉，Clorazepate會先decarboxylation 再 hydroxylation產生 3-hydroxydesmethyldiazepam(100-2)，Diazepam可代謝為Oxazepam。接下來就是C和D，Halazepam的特點是N上接CF3，下面的苯環沒有接東西，與Halazepam相比Flurazepam下面的苯環多接了F，也就是說可以合理推測Flurazepam就算怎麼代謝都不可能與Diazepam、Clorazepate、Halazepam一樣代謝為Oxazepam。再補個Oxazepam考古:51 下列 benzodiazepines 中，何者較適用於肝功能不良的病人？(101-1)(A) diazepam(B) fludiazepam(C) nimetazepam(D) oxazepam答案：D52 與 diazepam 相較，oxazepam 較適用於何種病人？(100-2)(A)肝功能不佳者(B)腎功能不佳者...

【用戶】Bryan

【年級】國三上

【評論內容】Flurazepam hydrochloride is rapidly absorbed from the G.I. tract. Flurazepam is rapidly metabolized and is excreted primarily in the urine. Following a single oral dose, peak Flurazepam plasma concentrations ranging from 0.5 to 4.0 ng/mL occur at 30 to 60 minutes post-dosing. The harmonic mean apparent half-life of Flurazepam is 2.3 hours.

【用戶】Bryan

【年級】國三上

【評論內容】Oxazepam, is a short-to-intermediate-acting 3-hydroxy benzodiazepine derivative.

【用戶】小藥渣(111-1新手藥師

【年級】大四上

【評論內容】補個路徑這題當下看到A、B兩個選頂可以先刪掉，Clorazepate會先decarboxylation 再 hydroxylation產生 3-hydroxydesmethyldiazepam(100-2)，Diazepam可代謝為Oxazepam。接下來就是C和D，Halazepam的特點是N上接CF3，下面的苯環沒有接東西，與Halazepam相比Flurazepam下面的苯環多接了F，也就是說可以合理推測Flurazepam就算怎麼代謝都不可能與Diazepam、Clorazepate、Halazepam一樣代謝為Oxazepam。再補個Oxazepam考古:51 下列 benzodiazepines 中，何者較適用於肝功能不良的病人？(101-1)(A) diazepam(B) fludiazepam(C) nimetazepam(D) oxazepam答案：D52 與 diazepam 相較，oxazepam 較適用於何種病人？(100-2)(A)肝功能不佳者(B)腎功能不佳者...