【用戶】Chris
【年級】高三下
【評論內容】• Papillary carcinoma (more than 85%):psammoma body and annie orphan nuclei• Follicular carcinoma (5% to 15%):• Anaplastic (undifferentiated) carcinomas (less than 5%)• Medullary carcinoma (5%; not derived from follicular epithelium)Medullary carcinoma is a neuroendocrine neoplasm; like normal C cells, these secrete calcitonin (and can also produce serotonin,ACTH, and vasoactive intestinal peptide [VIP]). Some 70% of cases are sporadic with the remainder occurring in the setting of MEN-2 syndromes or familial medullary thyroid carcinoma (FMTC). RET protooncogene mutations are involved in...