【用戶】Holmes
【年級】國一上
【評論內容】Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis. Hallmarks of this disease are microcytic hypochromic anemia, low transferrin saturation and normal/high serum hepcidin values.參考資料: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669438/課本p.46，靜脈注射鐵劑可能有血液學反應，但口服鐵劑無效...
【用戶】Holmes
【年級】國一上
【評論內容】Iron refractory iron deficiency anemia is a hereditary recessive anemia due to a defect in the TMPRSS6 gene encoding Matriptase-2. This protein is a transmembrane serine protease that plays an essential role in down-regulating hepcidin, the key regulator of iron homeostasis. Hallmarks of this disease are microcytic hypochromic anemia, low transferrin saturation and normal/high serum hepcidin values.參考資料: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669438/課本p.46，靜脈注射鐵劑可能有血液學反應，但口服鐵劑無效...